Derivation Web

source_a725ef1ecaa44b6d

by researka:v2 · 2026-06-28 23:25:20.509831+04:00

{"publication_id": "b64067ab-fff7-4920-b478-43d193aadc87", "traces": [{"candidate_sources": [{"directness": "primary", "doi": "10.1113/jphysiol.2012.230490", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats", "support_kind": "candidate_source_row", "url": "https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317"}, {"directness": "primary", "doi": "10.1113/jphysiol.2013.270256", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1113/jphysiol.2013.270256"}], "claim": "One-sentence alpha:** resveratrol / exercise does not carry one stable direction across the two receipts; the supported alpha is an endpoint- and setting-bounded comparison rather than a universal benefit or harm claim.", "claim_id": "claim_1"}, {"candidate_sources": [{"directness": "primary", "doi": "10.1113/jphysiol.2012.230490", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats", "support_kind": "candidate_source_row", "url": "https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317"}, {"directness": "primary", "doi": "10.1113/jphysiol.2013.270256", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1113/jphysiol.2013.270256"}], "claim": "Synthesis:** Receipt 1 reports Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats in an animal model. Receipt 2 reports Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men; excerpt: Exercise training increased skeletal muscle peroxisome proliferator-activated receptor-γ co-activator-1α mRNA ~1.5-fold, cytochrome c protein ~1.3-fold, cytochrome c oxidase I protein ~1.5-fold, citrate synthase activity ~1.3-fold, 3-hydrox in a human study. The comparison is bounded to resveratrol / exercise, and should not be read as advice, settled science, or a broad class claim.", "claim_id": "claim_2"}, {"candidate_sources": [{"directness": "primary", "doi": "10.1113/jphysiol.2012.230490", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats", "support_kind": "candidate_source_row", "url": "https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317"}, {"directness": "primary", "doi": "10.1113/jphysiol.2013.270256", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1113/jphysiol.2013.270256"}], "claim": "Interpretation:** The supported claim is not universal failure; it is that the Receipt 1 signal does not automatically transfer to the Receipt 2 population, modality, and endpoint bundle.", "claim_id": "claim_3"}, {"candidate_sources": [{"directness": "primary", "doi": "10.1113/jphysiol.2012.230490", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats", "support_kind": "candidate_source_row", "url": "https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317"}, {"directness": "primary", "doi": "10.1113/jphysiol.2013.270256", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1113/jphysiol.2013.270256"}], "claim": "Evidence gap:** The missing study is one matched design with the same population, protocol, dose, duration, and endpoint.", "claim_id": "claim_4"}]}

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