Derivation Web

source_c57d7d628ed245b7

by researka:v2 · 2026-06-20 09:29:06.411646+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Investigation of the regulatory effects of tea polyphenols on CYP450s in HepG2 cells,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"The Impact of Decaffeinated Green Tea Extract on Fat Oxidation, Body Composition and Cardio-Metabolic Health in Overweight, Recreationally Active Individuals",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE - ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study)",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Epigallocatechin Gallate (EGCG), an Active Phenolic Compound of Green Tea, Inhibits Tumor Growth of Head and Neck Cancer Cells by Targeting DNA Hypermethylation",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Painful Diabetic Neuropathy Is Associated with Compromised Microglial IGF-1 Signaling Which Can Be Rescued by Green Tea Polyphenol EGCG in Mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Epigallocatechin gallate enhances sympathetic heart rate variability and decreases blood pressure in obese subjects: a randomized control trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Catechin Plus Inulin Improves Insulin Resistance Without Reducing Visceral Fat and Shows Exploratory Gut Microbiota Signals in Adults with Visceral Obesity: A Double-Blind Randomized Controlled Trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
The effect of (-)-epigallocatechin gallate as an adjunct to non-surgical periodontal treatment: a randomized clinical trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Adipose-Derived Stem Cells Preincubated with Green Tea EGCG Enhance Pancreatic Tissue Regeneration in Rats with Type 1 Diabetes through ROS/Sirt1 Signaling Regulation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Gallation and B-Ring Dihydroxylation Increase Green Tea Catechin Residence Time in Plasma by Differentially Affecting Tissue-Specific Trafficking: Compartmental Model of Catechin Kinetics in Healthy Adults,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Effects of Standardized Green Tea Extract and Its Main Component, EGCG, on Mitochondrial Function and Contractile Performance of Healthy Rat Cardiomyocytes",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Administration of green tea polyphenols mitigates iron-overload-induced bone loss in a β-thalassemia mouse model,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Antimicrobial Activity of the Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate (EGCG) against Clinical Isolates of Multidrug-Resistant Vibrio cholerae,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Evaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Epigallocatechin-3-Gallate, the Main Polyphenol in Green Tea, Inhibits Porcine Epidemic Diarrhea Virus In Vitro",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effect of EGCG Extracted from Green Tea against Largemouth Bass Virus Infection,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
In Vitro Fermentation of Green Tea by Human Gut Microbiota Enhances Bioactivity and Bidirectionally Modulates Polyphenol Metabolites and Gut Microbiota,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
“Efficacy of cytotoxic effect of green tea catechins on the human periodontal fibroblasts and human dental pulp fibroblasts -An in vitro study”,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
3D printed PCLA scaffold with nano‐hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug‐resistant bacteria colonization,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Fibroids and unexplained infertility treatment with epigallocatechin gallate: a natural compound in green tea (FRIEND) – protocol for a randomised placebo-controlled US multicentre clinical trial of EGCG to improve fertility in women with uterine fibroids,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of Preeclampsia",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Spontaneous Osteogenic Differentiation of Human Mesenchymal Stem Cells by Tuna-Bone-Derived Hydroxyapatite Composites with Green Tea Polyphenol-Reduced Graphene Oxide,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Catechins and Human Health: Breakthroughs from Clinical Trials,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Microbial-Transferred Metabolites and Improvement of Biological Activities of Green Tea Catechins by Human Gut Microbiota,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Polyphenol EGCG Attenuates MDSCs-mediated Immunosuppression through Canonical and Non-Canonical Pathways in a 4T1 Murine Breast Cancer Model,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Polyphenol (-)-Epicatechin Pretreatment Mitigates Hepatic Steatosis in an In Vitro MASLD Model,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Iron Chelation Properties of Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Analysis on Tfr/Fth Regulations and Molecular Docking,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Assessment of Antioxidant, Immunomodulatory Activity of Oxidised Epigallocatechin-3-Gallate (Green Tea Polyphenol) and Its Action on the Main Protease of SARS-CoV-2—An In Vitro and In Silico Approach",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Green tea catechins and prostate cancer: mechanisms, clinical evidence, and safety: a narrative review",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"The Major Constituent of Green Tea, Epigallocatechin-3-Gallate (EGCG), Inhibits the Growth of HPV18-Infected Keratinocytes by Stimulating Proteasomal Turnover of the E6 and E7 Oncoproteins",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Integrating network pharmacology, bioinformatics and molecular docking to explore the anti-NSCLC mechanisms of EGCG in green tea",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Epigallocatechin-Gallate (EGCG): An Essential Molecule for Human Health and Well-Being,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The Green Tea Polyphenol Epigallocatechin-Gallate (EGCG) Interferes with Microcin E492 Amyloid Formation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Applications of a Standardized Green Tea Catechin Preparation for Viral Warts and Human Papilloma Virus-Related and Unrelated Cancers,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The green tea catechin EGCG provides proof-of-concept for a pan-coronavirus attachment inhibitor,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Significant Inactivation of SARS-CoV-2 In Vitro by a Green Tea Catechin, a Catechin-Derivative, and Black Tea Galloylated Theaflavins",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG): A Time for a New Player in the Treatment of Respiratory Diseases?,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Research Progress on the Protective Effect of Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG) on the Liver,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
A green tea extract catechin EGCg: Therapeutic potential for pediatric cardiomyopathies,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Therapeutic Potential of EGCG, a Green Tea Polyphenol, for Treatment of Coronavirus Diseases",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Epigenetic regulators polyphenols in neurodegenerative diseases: a promising intervention strategy,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Tea Polyphenol Epigallocatechin Gallate and the Gut–Health Axis: Unraveling Structural Characteristics, Metabolic Pathways, and Systemic Benefits",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"EGCG, a Green Tea Catechin, as a Potential Therapeutic Agent for Symptomatic and Asymptomatic SARS-CoV-2 Infection",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Osteoprotective Roles of Green Tea Catechins,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Scientific opinion on the safety of green tea catechins,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea ( Camellia sinensis L.) cv. “Yabukita” and “Sunrouge” on Eyestrain and Blood Pressure in Healthy Adults",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Epigallocatechin Gallate (EGCG) Is the Most Effective Cancer Chemopreventive Polyphenol in Green Tea,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Hydrogen sulphide donors selectively potentiate a green tea polyphenol EGCG-induced apoptosis of multiple myeloma cells,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"The Dual Action of Epigallocatechin Gallate (EGCG), the Main Constituent of Green Tea, against the Deleterious Effects of Visible Light and Singlet Oxygen-Generating Conditions as Seen in Yeast Cells",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Green Tea Catechin, EGCG, Suppresses PCB 102-Induced Proliferation in Estrogen-Sensitive Breast Cancer Cells",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2 α /ATF4 and IRE1 α,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Polyphenols Ameliorate the Early Renal Damage Induced by a High-Fat Diet via Ketogenesis/SIRT3 Pathway,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Green Tea Polyphenol (−)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Protein Binding Characteristics of the Principal Green Tea Catechins: A QCM Study Comparing Crude Extract to Pure EGCG,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Function of Green Tea Catechins in the Brain: Epigallocatechin Gallate and its Metabolites,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Polyphenols: Benefits to the Cardiovascular System in Health and in Aging,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Conformation and Aggregation of Human Serum Albumin in the Presence of Green Tea Polyphenol (EGCg) and/or Palmitic Acid,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"The green tea polyphenol, (−)‐epigallocatechin‐3‐gallate, inhibits obesity and metabolic syndrome in high‐fat fed mice",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Health Benefits of Polyphenols and Carotenoids in Age-Related Eye Diseases,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
In Vitro and In Silico Studies of the Molecular Interactions of Epigallocatechin-3- O -gallate (EGCG) with Proteins That Explain the Health Benefits of Green Tea,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Tea Polyphenols in Promotion of Human Health,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Targeting Bacterial Biofilms by the Green Tea Polyphenol EGCG,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
A Review of the Antiviral Role of Green Tea Catechins,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Effect of chlorhexidine, green tea and egcg as therapeutic primers to increase the durability of resin-dentin bond",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Studenski 2011,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cesari 2009,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Perera 2006,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
WHO 2000,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Bohannon 1997,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cruz-Jentoft 2019,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Owen 2000,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Anisimov 2008,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Tinetti 1988,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Tancredi 2015,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Ioannidis 2005,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

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