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# Alpha memo: nicotinamide exercise performance
**One-sentence alpha:** Nicotinamide riboside (NR) supplementation may improve redox homeostasis and exercise performance in older adults with low baseline NAD(P)H, while failing to produce benefit—and potentially trending toward worse performance—in young, NAD(P)H-replete rats, suggesting baseline status as a tentative moderator.
**Receipt 1:** *The…