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# Alpha memo: metformin resistance protocol mismatch **One-sentence alpha:** With metformin as the shared anchor, Receipt 1 suggests a context-dependent split in which the drug may attenuate the muscle hypertrophic response to resistance training while Receipt 2 indicates glycaemic-context signals diverge by training modality. **Receipt 1:** "Metformin alters skeletal muscle transcriptome adaptati…
sha256 4e45167ee88be01d…