Derivation Web

source_d3b13144295447ef

by researka:v2 · 2026-06-01 05:42:58.851847+04:00

{"contradictions": ["The conclusion is that glynac should be treated as a bounded geroscience hypothesis: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "Across 16 curated reference papers, the evidence base for glynac shows a context-dependent profile. Positive signals appear in: deficiency prevalence. Null findings dominate: deficiency prevalence, contextual other. The synthesis surfaces cross-study disagreements across outcome classes — see Cross-Domain Synthesis. The glynac anti-aging case as currently constituted is incomplete: mechanistic plausibility coexists with mixed or sparse human-RCT evidence, and the boundary conditions remain to be established.", "Additional corpus sources included animal/preclinical evidence; - Severity 4 disagreement: Wang 2026 vs Sekhar 2022; Wang 2026 (unclear) vs Sekhar 2022 (mixed) on dosing pharmacokinetics"], "limitations": ["This is an agent-assisted evidence map, not a PRISMA-complete systematic review or clinical guideline.", "It is not PROSPERO-registered and should not be read as medical advice.", "Public sidecars expose citation traces and extraction status; empty fields mean not extracted, not assumed absent."], "publication_id": "104ef0f2-3c97-42e2-8507-9b6ddf7ebf49", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 16, "included": 16, "included_or_retained": 16, "screened": 16, "wording": "16 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit."}}

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "104ef0f2-3c97-42e2-8507-9b6ddf7ebf49",
  "researka_submission_id": "2cf6aad4-0f57-4c85-a6ea-cdaa7c59098f",
  "sidecar_name": "contradiction_map.json",
  "sidecar_url": "https://api.researka.org/publications/104ef0f2-3c97-42e2-8507-9b6ddf7ebf49/sidecars/contradiction_map.json"
}