Derivation Web

v0.1 · api
source · application/json

source_d548b78549d7446c

sha256 87f1beafa263578bed84d84ec55032a33b2c60d38812eedda6c795e6e9396435

by researka:v2 · 2026-06-23 12:28:23.594470+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "99bae081-2617-48d1-8627-0786168ef5e1", "sources": [{"directness": "primary", "doi": "10.1111/iwj.70856", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy for Chronic Venous Leg Ulcers: A Prospective Randomised Controlled Trial"}, {"directness": "primary", "doi": "10.1186/s12873-025-01410-w", "risk_of_bias": "not appraised in public sidecar", "study": "Serum lactate and carboxyhemoglobin as predictors of hyperbaric oxygen therapy in carbon monoxide poisoning: a retrospective study"}, {"directness": "primary", "doi": "10.1136/bmjopen-2025-112284", "risk_of_bias": "not appraised in public sidecar", "study": "HOTFy: randomised clinical trial for hyperbaric oxygen therapy in fibromyalgia"}, {"directness": "primary", "doi": "10.3390/jcm14092984", "risk_of_bias": "not appraised in public sidecar", "study": "Risk Factors for Middle Ear Barotrauma in Patients with Carbon Monoxide Poisoning Undergoing Monoplace Hyperbaric Oxygen Therapy: A Retrospective Cohort Study"}, {"directness": "primary", "doi": "10.3389/fneur.2026.1775204", "risk_of_bias": "not appraised in public sidecar", "study": "The awakening effect of hyperbaric oxygen therapy combined with systematic auditory stimulation in comatose patients with craniocerebral injury and its influence on serum biomarkers"}, {"directness": "primary", "doi": "10.3390/jcm15051725", "risk_of_bias": "not appraised in public sidecar", "study": "Phase-Specific Changes in Vital Signs and Electrocardiogram Findings During Hyperbaric Oxygen Therapy in Hemodynamically Stable Patients: A Prospective Observational Study"}, {"directness": "review-level", "doi": "10.3389/fmed.2025.1632414", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy for radiation enteritis and clinical parameters: a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.3390/brainsci16020165", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy in Traumatic and Non-Traumatic Spinal Cord Injuries: Insights from Nearly Five Decades of Evidence with Single-Center Experience"}, {"directness": "primary", "doi": "10.3390/jfb17050209", "risk_of_bias": "not appraised in public sidecar", "study": "Do Different Durations of Hyperbaric Oxygen Therapy Affect the Microleakage of Bulk-Fill Composites?"}, {"directness": "primary", "doi": "10.3389/fmed.2025.1706637", "risk_of_bias": "not appraised in public sidecar", "study": "Clinical efficacy and mechanisms of hyperbaric oxygen therapy in the treatment of rheumatic and immune diseases"}, {"directness": "primary", "doi": "10.1515/med-2025-1351", "risk_of_bias": "not appraised in public sidecar", "study": "Optimizing hyperbaric oxygen initiation time in carbon monoxide poisoning: a 3-hour window enhances neurological recovery via lactate clearance"}, {"directness": "primary", "doi": "10.1097/MD.0000000000044893", "risk_of_bias": "not appraised in public sidecar", "study": "Hematological safety of hyperbaric oxygen therapy in oncology: Stratified analysis by chemotherapy and herbal medicine use"}, {"directness": "primary", "doi": "10.3389/fneur.2025.1641033", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study"}, {"directness": "primary", "doi": "10.3390/healthcare13020128", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy in the Treatment of Crohn’s Disease"}, {"directness": "primary", "doi": "10.3389/fneur.2026.1690633", "risk_of_bias": "not appraised in public sidecar", "study": "The effect of hyperbaric oxygen therapy on sleep quality across diverse patient populations"}, {"directness": "review-level", "doi": "10.3390/jcm15072628", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy Versus Intravenous Thrombolysis in the Treatment of Central Retinal Artery Occlusion: A Systematic Review and Meta-Analysis"}, {"directness": "review-level", "doi": "10.1002/ams2.70114", "risk_of_bias": "not appraised in public sidecar", "study": "Evaluating the Efficacy of Hyperbaric Oxygen Therapy for Acute Carbon Monoxide Poisoning: A Systematic Review and Meta‐Analysis"}, {"directness": "review-level", "doi": "10.1093/jbcr/irag026", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy in Burn Care: A Systematic Review of Current Evidence"}, {"directness": "primary", "doi": "10.3390/s26061794", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of Hyperbaric Oxygen Therapy on Cerebral Activity in Stroke Patients Based on fNIRS"}, {"directness": "primary", "doi": "10.37796/2211-8039.1693", "risk_of_bias": "not appraised in public sidecar", "study": "Adjunctive hyperbaric oxygen therapy for chronic diabetic foot ulcer unresponsive to standard care: A case report"}, {"directness": "primary", "doi": "10.4103/nah.nah_19_24", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of Hyperbaric Oxygen Therapy Combined with Music Therapy on Brain Function and Mental Health of Patients with Aneurismal Subarachnoid Hemorrhage: A Retrospective Study"}, {"directness": "review-level", "doi": "10.3390/medicina62010109", "risk_of_bias": "not appraised in public sidecar", "study": "Comparative Evidence on Negative Pressure Therapy and Hyperbaric Oxygen Therapy for Diabetic Foot Ulcers: A Systematic Review of Independent Effectiveness and Clinical Applicability"}, {"directness": "primary", "doi": "10.1093/jbcr/irag033.192", "risk_of_bias": "not appraised in public sidecar", "study": "1004. Case Study. Multimodal Plantar Reconstruction Using Dermal Substitutes, Hyperbaric Oxygen, and Negative Pressure Wound Therapy"}, {"directness": "primary", "doi": "10.4103/mgr.MEDGASRES-D-24-00111", "risk_of_bias": "not appraised in public sidecar", "study": "Application of hyperbaric oxygen therapy in the treatment of spinal cord injury: insights from preclinical to clinical evidence"}, {"directness": "primary", "doi": "10.1093/milmed/usaf100", "risk_of_bias": "not appraised in public sidecar", "study": "Rapid Initiation of Hyperbaric Oxygen Therapy for Multiple Simultaneous Cases of Acute Carbon Monoxide Poisoning at a Single Center"}, {"directness": "primary", "doi": "10.1136/bmjopen-2024-087164", "risk_of_bias": "not appraised in public sidecar", "study": "Efficacy and safety of hyperbaric oxygen therapy for Parkinson’s disease with cognitive dysfunction: protocol for a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.3390/pathophysiology33010018", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric Oxygen Therapy in Experimental Autoimmune Myocarditis: Insights from Preclinical Models to Translational Perspectives"}, {"directness": "review-level", "doi": "10.1093/jbcr/irag033.264", "risk_of_bias": "not appraised in public sidecar", "study": "825. Hyperbaric Oxygen Therapy in Burn Care: A Systematic Review of Current Evidence"}, {"directness": "primary", "doi": "10.3389/fragi.2021.678543", "risk_of_bias": "not appraised in public sidecar", "study": "Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia"}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}, {"directness": "citation", "doi": "10.1371/journal.pmed.0020124", "risk_of_bias": "not appraised in public sidecar", "study": "Ioannidis 2005"}]}
metadata
{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "99bae081-2617-48d1-8627-0786168ef5e1",
  "researka_submission_id": "713116bf-d799-4bd3-a19c-4fe782b8a3a1",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/99bae081-2617-48d1-8627-0786168ef5e1/sidecars/risk_of_bias.json"
}

view full chain →