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# Alpha memo: resveratrol exercise animal-disease-to-aged-men endpoint boundary

**Research question:** How far does the Receipt 1 signal transfer across the setting tested by Receipt 2?

**One-sentence alpha:** Receipt 1 supports a combined-protocol cardiac/aortic signal in animal-disease; Receipt 2 separates the components and limits transfer to skeletal/metabolic in aged-men.

**Receipt 1:** Be…