Derivation Web

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source_d9eab6b93ab14103

sha256 d825375b01cbeeea92f9f5ed7b98453551b285fa9c10860a46d04061e727f585

by researka:v2 · 2026-06-03 10:46:29.112323+04:00

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The context receipts provide source breadth and boundary checks, not independent confirmation of the lead claim.", "claim_id": "claim_1"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.", "claim_id": "claim_2"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "Real tension: the useful signal is narrower than the topic label. The lead receipts support the core claim, while the added A/B context receipts define where that claim may generalize, fail, or need a separate extraction.", "claim_id": "claim_3"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "Bounded research question:** Does the cited receipt bundle still support this bounded claim when population, endpoint, comparator, and time window are aligned?", "claim_id": "claim_4"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "_Boundary evidence only; these receipts broaden source context but do not independently prove the lead claim._", "claim_id": "claim_5"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "`fact_id=187886` (`B_context`) — Klotho concentration increased significantly after chronic exercise training (minimum of 12 weeks) (Hedge' g [95%CI] 1.3 [0.69-1.90]; P < 0.0001) doi=10.1038/s41598-022-22123-1", "claim_id": "claim_6"}, {"candidate_sources": [{"doi": "10.1155/2015/406269", "study": "Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients", "url": null}, {"doi": "10.1371/journal.pone.0100688", "study": "Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients.", "url": null}, {"doi": "10.5414/cn107800", "study": "The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.", "url": null}, {"doi": "10.1186/s12882-019-1391-1", "study": "Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis", "url": null}, {"doi": "10.1097/shk.0b013e3182845445", "study": "Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice.", "url": null}], "claim": "_Within the currently bound receipt bundle, no A_core/B_context opposing fact was selected. Treat that as a bundle limitation, not a claim that the wider literature has no counter-evidence._", "claim_id": "claim_7"}]}
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