Derivation Web

source_df5e488a721c4f5f

by researka:v2 · 2026-06-25 04:51:43.735101+04:00

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( mechanistic ablation supports the topic effect; not a comparator outcome)", "type": "claim"}, {"id": "claim_4", "text": "Specific moderators in this bundle are population/indication (STZ-induced diabetic rats; mice; mouse and cell models; streptozotocin-induced diabetic rats; streptozotocin-nicotinamide (STZ-NA)-induced diabetic mice), study design/evidence type (primary).", "type": "claim"}, {"id": "claim_5", "text": "The selected receipts group because each carries a fact-level extraction for quercetin; they separate by context (animal model) and endpoint, so they are not interchangeable evidence for one pooled claim.", "type": "claim"}, {"id": "claim_6", "text": "The signal is purely descriptive of effect-direction heterogeneity; it cannot support even a weak causal or comparative-efficacy inference, and pooling across these PICOs would be inappropriate.", "type": "claim"}, {"comparator": "not extracted", "directness": "primary", "doi": "10.4236/jdm.2012.21013", "effect": "not extracted", "endpoint": "not extracted", "id": "source_1", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Effect of quercetin on postprandial glucose excursion after mono- and disaccharides challenge in normal and diabetic rats", "type": "source", "url": "https://doi.org/10.4236/jdm.2012.21013", "year": 2012}, {"comparator": "not extracted", "directness": "primary", "doi": "10.3390/nu8010027", "effect": "not extracted", "endpoint": "not extracted", "id": "source_2", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Quercetin Attenuates Chronic Ethanol-Induced Hepatic Mitochondrial Damage through Enhanced Mitophagy", "type": "source", "url": "https://doi.org/10.3390/nu8010027", "year": 2016}, {"comparator": "not extracted", "directness": "primary", "doi": "10.3390/metabo13010130", "effect": "not extracted", "endpoint": "not extracted", "id": "source_3", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats", "type": "source", "url": "https://doi.org/10.3390/metabo13010130", "year": 2023}, {"comparator": "not extracted", "directness": "primary", "doi": "10.3390/ph17060757", "effect": "not extracted", "endpoint": "not extracted", "id": "source_4", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Quercetin and Kaempferol as Multi-Targeting Antidiabetic Agents against Mouse Model of Chemically Induced Type 2 Diabetes", "type": "source", "url": "https://doi.org/10.3390/ph17060757", "year": 2024}, {"comparator": "not extracted", "directness": "primary", "doi": "10.3892/ijmm.2023.5321", "effect": "not extracted", "endpoint": "not extracted", "id": "source_5", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Quercetin alleviates lipopolysaccharide‑induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway", "type": "source", "url": "https://doi.org/10.3892/ijmm.2023.5321", "year": 2023}], "publication_id": "d3b70206-291b-45c9-b804-ee73aaf10692", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 5, "included": 5, "included_or_retained": 5, "screened": 5, "wording": "5 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit."}}

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