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source_e218439be98448f8

sha256 161942702a572845d4c35f8397712f82b8f2389e655aa11d86f8df980e980a91

by researka:v2 · 2026-06-09 09:20:00.063082+04:00

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"risk_of_bias": "not appraised in public sidecar", "study": "Investigation of Statin Medication Use in Elderly Patients with Cardiovascular Disease on Regular Physical Examination and the Relationship with Glucolipid Metabolism and Adverse Cardiovascular Prognosis"}, {"directness": "primary", "doi": "10.1093/braincomms/fcae195", "risk_of_bias": "not appraised in public sidecar", "study": "Statin use and risk of Parkinson’s disease among older adults in Japan: a nested case–control study using the Longevity Improvement and Fair Evidence study"}, {"directness": "primary", "doi": "10.3904/kjim.2024.085", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of statin use on serum creatinine phosphokinase levels in normal thyroid function"}, {"directness": "primary", "doi": "10.1016/j.hrtlng.2023.03.005", "risk_of_bias": "not appraised in public sidecar", "study": "Impact of In-hospital Statin Use on Mortality in COVID-19 Patients from a Majority African American 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adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}, {"directness": "citation", "doi": "10.1001/jama.2010.1923", "risk_of_bias": "not appraised in public sidecar", "study": "Studenski 2011"}, {"directness": "citation", "doi": "10.1093/gerona/glp012", "risk_of_bias": "not appraised in public sidecar", "study": "Cesari 2009"}, {"directness": "citation", "doi": "10.1111/j.1532-5415.2006.00701.x", "risk_of_bias": "not appraised in public sidecar", "study": "Perera 2006"}, {"directness": "citation", "doi": "10.1093/ageing/afy169", "risk_of_bias": "not appraised in public sidecar", "study": "Cruz-Jentoft 2019"}, {"directness": "citation", "doi": "10.1371/journal.pmed.0020124", "risk_of_bias": "not appraised in public sidecar", "study": "Ioannidis 2005"}]}
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}

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