Derivation Web

source_e858906634a04472

# Source literature boundary memo

## Research question

Across retrieved source-level receipts for metformin treatment, which endpoints show directionally favorable versus null/non-convergent signals, and what matched PICO remains untested?

## Selection criteria

The source-literature selector kept metformin treatment because the candidate bundle met the public source rule: 5 citable papers, 5 d…