Derivation Web

source_fd8bfc4a07cd4443

by researka:v2 · 2026-07-14 17:23:36.967441+04:00

# Alpha memo: The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training

Hypothesis-level alpha signal; not clinical advice.

**Alpha hypothesis:** In collagen peptides resistance training tendon muscle adaptation trial, direct human randomized trial and intervention study receipts support a bounded negative and null signal across accuracy and error; treat it as hypothesis-level until the same population and endpoint are replicated.

**Core signal:**
The direct human receipts are randomized trial and intervention study evidence for accuracy and error.
Because the recorded directions are negative and null, this memo treats the bundle as endpoint-specific evidence rather than a pooled clinical effect.

**Receipt-level synthesis:**
- Publication metadata: source records report 10.1249/MSS.0000000000003242 (2023) and `https://openalex.org/W7113114512` (2025); these are article publication years, not trial dates.
- 10.1249/MSS.0000000000003242 - randomized trial in human; endpoint: The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training; direction: negative. Source title: The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training
- `https://openalex.org/W7113114512`: intervention study in human; endpoint: accuracy and error; direction: null. Source title: Correction: The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training

**Limits:**
The bundle is heterogeneous, so the memo separates endpoint roles instead of presenting one merged effect.
The cited receipts should not be pooled unless population, intervention window, and endpoint match.
A same-endpoint human replication would move this from alpha signal toward claim-level evidence.

**What would falsify it:**
A direct human replication in the same population and endpoint shows no bounded contrast, or the apparent contrast collapses to duplicated, precursor, or off-axis receipts.

**Receipts:**
1. 10.1249/MSS.0000000000003242 The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training, 2023, Medicine & Science in Sports & Exercise. Source: fullraw:semantic_scholar. ID: https://doi.org/10.1249/MSS.0000000000003242
2. `https://openalex.org/W7113114512` Correction: The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training, 2025. Source: fullraw:openalex. ID: https://openalex.org/W7113114512

{
  "article_type": "alpha_memo",
  "domain_slug": "longevity_research",
  "researka_object_type": "submission",
  "researka_submission_id": "9a21725e-2fe8-4926-b688-cc5b33ac299f",
  "title": "The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training"
}