Derivation Web

source_ffce6d1055324b9e

by researka:v2 · 2026-06-27 23:06:40.077277+04:00

{"content_hash": null, "edges": [{"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_1", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_2", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_3", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_4", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_5", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_6", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_7", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_8", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_9", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_10", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_11", "type": "contains_claim"}, {"from": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "to": "claim_12", "type": "contains_claim"}], "nodes": [{"id": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "title": "resistance training: one bounded, context-dependent signal across receipts", "type": "publication"}, {"id": "claim_1", "text": "Across retrieved source-level receipts for resistance_training, which endpoints show directionally favorable versus null/non-convergent signals, and what matched PICO remains untested?", "type": "claim"}, {"id": "claim_2", "text": "Finding: RT+CR+AT produced significantly greater increases in leg muscle strength [4.9 (0.7, 9.0) versus –1.1 (–5.5, 3.2) Nm, P =0.05]", "type": "claim"}, {"id": "claim_3", "text": "Finding: An increase in intramuscular fat was only observed in the CG (p < 0.01, 1.06; large)", "type": "claim"}, {"id": "claim_4", "text": "Finding: resistance training exercise increased lean body mass assessed from dual-energy X-ray absorptiometry [mean difference (MD): +1.07 kg, 95% CI: 0.76-1.37; P < 0.001]", "type": "claim"}, {"id": "claim_5", "text": "This receipt-backed scoping note has one bounded signal: resistance_training shows endpoint-specific favorable signals with context limits across this 5-source primary/review bundle (2018-2022). Grouped by direction: directionally favorable: 3 receipt(s) | other/mixed: 2 receipt(s). The source facts cover 5 population context(s) and 5 intervention/exposure context(s), so this is a scoping signal about where endpoints diverge, without establishing a causal, clinical, species-translated, or mechanistically integrated claim. The listed effect sizes remain source-specific across endpoints and populations; they are not pooled or averaged. This is a heterogeneous indication/context map, not a unified disease-specific or endpoint-family claim. Concrete source-level examples: Interventions involving resistance training and caloric restriction were the most effective for reducing body fat percentage; RT+CR+AT produced significantly greater increases in leg muscle strength [4.9 (0.7, 9.0) versus –1.1 (–5.5, 3.2) Nm, P =0.05]; An increase in intramuscular fat was only observed in the CG (p < 0.01, 1.06; large).", "type": "claim"}, {"id": "claim_6", "text": "null/non-convergent or other/mixed: the extracted fact is null, mixed, or not directionally interpretable.", "type": "claim"}, {"id": "claim_7", "text": "directionally favorable: A Randomized, Controlled Trial of Resistance Training Added to Caloric Restriction Plus Aerobic Exercise Training in Obese Heart Failure With Preserved Ejection Fraction — RT+CR+AT produced significantly greater increases in leg muscle strength [4.9 (0.7, 9.0) versus –1.1 (–5.5, 3.2) Nm, P =0.05]", "type": "claim"}, {"id": "claim_8", "text": "other/mixed: Effects of 16 Weeks of Resistance Training on Muscle Quality and Muscle Growth Factors in Older Adult Women with Sarcopenia: A Randomized Controlled Trial — An increase in intramuscular fat was only observed in the CG (p < 0.01, 1.06; large)", "type": "claim"}, {"id": "claim_9", "text": "directionally favorable: The evolution of body composition in oncology—epidemiology, clinical trials, and the future of patient care: facts and numbers — resistance training exercise increased lean body mass assessed from dual-energy X-ray absorptiometry [mean difference (MD): +1.07 kg, 95% CI: 0.76-1.37; P < 0.001]", "type": "claim"}, {"id": "claim_10", "text": "Specific moderators in this bundle are population/indication (individuals with overweight and obesity; obese elderly individuals; older adult women aged over 65 with sarcopenia; older patients with obese heart failure with preserved ejection fraction; patients with non-metastatic cancer (meta-analysis of 6 RCTs)), study design/evidence type (primary/review). Single primary-study estimates are separated from pooled review or meta-analytic estimates rather than treated as interchangeable.", "type": "claim"}, {"id": "claim_11", "text": "The selected receipts group because each carries a fact-level extraction for resistance_training; they separate by context (human clinical/observational and other source context) and endpoint, so they are not interchangeable evidence for one pooled claim.", "type": "claim"}, {"id": "claim_12", "text": "The signal is purely descriptive of effect-direction heterogeneity; it cannot support even a weak causal or comparative-efficacy inference, and pooling across these PICOs would be inappropriate.", "type": "claim"}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.1111/obr.13428", "effect": "not extracted", "endpoint": "not extracted", "id": "source_1", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta‐analysis", "type": "source", "url": "https://doi.org/10.1111/obr.13428", "year": 2022}, {"comparator": "not extracted", "directness": "primary", "doi": "10.1161/circheartfailure.122.010161", "effect": "not extracted", "endpoint": "not extracted", "id": "source_2", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "A Randomized, Controlled Trial of Resistance Training Added to Caloric Restriction Plus Aerobic Exercise Training in Obese Heart Failure With Preserved Ejection Fraction", "type": "source", "url": "https://doi.org/10.1161/circheartfailure.122.010161", "year": 2022}, {"comparator": "not extracted", "directness": "primary", "doi": "10.3390/ijerph18136762", "effect": "not extracted", "endpoint": "not extracted", "id": "source_3", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of 16 Weeks of Resistance Training on Muscle Quality and Muscle Growth Factors in Older Adult Women with Sarcopenia: A Randomized Controlled Trial", "type": "source", "url": "https://doi.org/10.3390/ijerph18136762", "year": 2021}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.3390/nu10040423", "effect": "not extracted", "endpoint": "not extracted", "id": "source_4", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Resistance Training Prevents Muscle Loss Induced by Caloric Restriction in Obese Elderly Individuals: A Systematic Review and Meta-Analysis", "type": "source", "url": "https://doi.org/10.3390/nu10040423", "year": 2018}, {"comparator": "not extracted", "directness": "primary", "doi": "10.1002/jcsm.12379", "effect": "not extracted", "endpoint": "not extracted", "id": "source_5", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "The evolution of body composition in oncology—epidemiology, clinical trials, and the future of patient care: facts and numbers", "type": "source", "url": "https://doi.org/10.1002/jcsm.12379", "year": 2018}], "publication_id": "e9c06f33-86bb-4497-8e60-af3e57bf3cfa", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 5, "included": 5, "included_or_retained": 5, "screened": 5, "wording": "5 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit."}}

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