Derivation Web

claim_0d384597e97243b1

# Research Synthesis: Intermittent Fasting — full paper

## Abstract

Evidence-honesty note: 47/60 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

This paper synthesizes evidence on intermittent fasting if effects across 60 included source papers and…

source_b09dab916e3646c3

# Research Synthesis: Intermittent Fasting — full paper

## Abstract

Evidence-honesty note: 47/60 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

This paper synthesizes evidence on intermittent fasting if effects across 60 included source papers and…

source_ecbcc52bc25545f7

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source_be5ab6d4b1554f9f

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source_262b3d6cfae44e0d

{"contradictions": ["Positive study-level signals are not the dominant direction in any outcome class; null signals are not the dominant direction in any outcome class; negative signals are not the dominant direction in any outcome class; mixed or heterogeneous signals are summarized in the cardiometabolic, contextual adjacent evidence, immune and inflammation, muscle function, mechanism, and safe…

source_c587886596d141cc

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Comparative effects of intermittent fasting and calorie restriction on cardiovascular health in adults with overweight or obesity,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effects of Intermittent Fasting and Calorie Restriction on Exerci…

source_1ad8532b204e4e3e

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "7e5ce8c6-78d4-4732-b449-7c9ff84676ce", "sources": [{"directness": "primary", "doi": "10.1038/s41598-025-32673-9", "risk_of_bias": "not appraised in public sidecar", "study": "Comparative effects of intermittent fasting and calorie restri…

source_ec522d828d584bb4

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}