Derivation Web

claim_7305186dfcfe425c

# Research Synthesis: Alpha-glucosidase inhibitor — full paper

## Abstract

Evidence-honesty note: 12/14 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

This paper synthesizes evidence on Alpha-glucosidase inhibitor across 14 included source papers …

source_83d2a5fb0790441a

# Research Synthesis: Alpha-glucosidase inhibitor — full paper

## Abstract

Evidence-honesty note: 12/14 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

This paper synthesizes evidence on Alpha-glucosidase inhibitor across 14 included source papers …

source_35654cfb3c3d44af

{"publication_id": "08943c0f-97ab-41e2-820b-bf2dbe384513", "traces": [{"candidate_sources": [{"doi": "10.1186/s40360-023-00706-6", "study": "The effect of acarbose on lipid profiles in adults: a systematic review and meta-analysis of randomized clinical trials", "url": "https://doi.org/10.1186/s40360-023-00706-6"}, {"doi": "10.1038/s41598-021-84015-0", "study": "The effects of acarbose therapy on …

source_a3c78babef194a8d

{"content_hash": "sha256:4aeef3b76bc436fe882355a42ded1aa046f2393f2ee57c9b5a8de2973df418a3", "edges": [{"from": "08943c0f-97ab-41e2-820b-bf2dbe384513", "to": "claim_1", "type": "contains_claim"}, {"from": "08943c0f-97ab-41e2-820b-bf2dbe384513", "to": "claim_2", "type": "contains_claim"}, {"from": "08943c0f-97ab-41e2-820b-bf2dbe384513", "to": "claim_3", "type": "contains_claim"}, {"from": "08943c0f-…

source_458b3a5d57674ac2

{"contradictions": ["Positive study-level signals are not the dominant direction in any outcome class; null signals are summarized in the contextual adjacent evidence outcome class; negative signals are not the dominant direction in any outcome class; mixed or heterogeneous signals are summarized in the cardiometabolic and longevity outcome classes. The paper therefore interprets the corpus as a t…

source_e9d1f957f712489a

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
The effect of acarbose on lipid profiles in adults: a systematic review and meta-analysis of randomized clinical trials,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
The effects of acarbose therapy on reductions of myocardial infarction…

source_275870f6cb3a4fa1

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "08943c0f-97ab-41e2-820b-bf2dbe384513", "sources": [{"directness": "review-level", "doi": "10.1186/s40360-023-00706-6", "risk_of_bias": "not appraised in public sidecar", "study": "The effect of acarbose on lipid profiles in adults: a sys…

source_40129f8ddc6647f0

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}