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# Alpha memo: Resveratrol + exercise may lose or invert the liver/cardiovascular signal between mature-mouse models and older adults
**One-sentence alpha:** Resveratrol added to exercise appears to support liver anti-aging readouts in mature SAMP8 mice, but in older adults a 12-week combined intervention failed to translate into a clean TMAO/CVD-risk benefit, suggesting context-dependent decouplin…
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