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# Alpha memo: Split response of nicotinamide riboside on exercise performance by age **One-sentence alpha:** Nicotinamide riboside (NR) supplementation may shift from performance-impairing in young rats to performance-improving in older humans when baseline NAD(P)H status is low. **Receipt 1:** "The NAD+ precursor nicotinamide riboside decreases exercise performance in rats" — In a 21-day gavage p…
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