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# Urolithin A Endurance Efficacy ## Signal Urolithin A improves muscle strength, aerobic endurance, and physical performance in middle-aged adults. [R1] ## Update Urolithin A failed to significantly improve 6-minute walk distance and maximal ATP production in adults aged 65 to 90. [R2] ## Synthesis Efficacy varies by age cohort, with benefits observed in middle-aged adults but absent for pri…
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