Derivation Web

claim_8658f2e4cd094038

# Hypothesis-Generating Brief: Statins longevity — full paper
## Abstract

Evidence-honesty note: 32/53 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statement…

source_54c37f6f76e14b11

# Hypothesis-Generating Brief: Statins longevity — full paper
## Abstract

Evidence-honesty note: 32/53 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statement…

source_3a28de96fe5446da

{"publication_id": "e7c852f1-873a-4cb5-98d6-2f49fad6de83", "traces": [{"candidate_sources": [{"doi": "10.1186/s40246-025-00753-6", "study": "Pharmacogenomic insights into atorvastatin and rosuvastatin adverse effects: a prospective observational study in the UAE’s multiethnic population", "url": "https://doi.org/10.1186/s40246-025-00753-6"}, {"doi": "10.1186/s12876-025-04398-6", "study": "The impa…

source_ad39ec4973274d0c

{"content_hash": "sha256:aa1028d01910aadc9b5f8f50adfc6184b4c6da854f9f9737f9e1858c1b233e55", "edges": [{"from": "e7c852f1-873a-4cb5-98d6-2f49fad6de83", "to": "claim_1", "type": "contains_claim"}, {"from": "e7c852f1-873a-4cb5-98d6-2f49fad6de83", "to": "claim_2", "type": "contains_claim"}, {"from": "e7c852f1-873a-4cb5-98d6-2f49fad6de83", "to": "claim_3", "type": "contains_claim"}, {"from": "e7c852f1-…

source_48cb445cef074123

{"contradictions": ["The corpus contains 3 direct clinical sources, 49 adjacent clinical sources, and 1 mechanistic or model-system source. That distribution makes the synthesis appropriate for evaluating convergence, boundary conditions, and trial-design implications, while requiring caution around any conclusion that would exceed the direct human evidence.", "The thesis is: Across 53 curated ref…

source_56c90ffdd5f24057

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Pharmacogenomic insights into atorvastatin and rosuvastatin adverse effects: a prospective observational study in the UAE’s multiethnic population,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The impact of statin use on colorectal cancer pr…

source_ed4dce26d5d641f5

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "e7c852f1-873a-4cb5-98d6-2f49fad6de83", "sources": [{"directness": "primary", "doi": "10.1186/s40246-025-00753-6", "risk_of_bias": "not appraised in public sidecar", "study": "Pharmacogenomic insights into atorvastatin and rosuvastatin ad…

source_8bf8e39bb99743fc

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}