Derivation Web

claim_a2b99d84ab304dac

# Research Synthesis: Longevity Metabolism Effects — full paper

## Abstract

Evidence-honesty note: 23/25 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statem…

source_6888122e9319462a

# Research Synthesis: Longevity Metabolism Effects — full paper

## Abstract

Evidence-honesty note: 23/25 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statem…

source_9daabaee5bc64220

{"publication_id": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "traces": [{"candidate_sources": [{"doi": "10.1007/s11357-025-01839-8", "study": "Effects of resistance-based training and polyphenol supplementation on physical function, metabolism, and inflammation in aging individuals", "url": "https://doi.org/10.1007/s11357-025-01839-8"}, {"doi": "10.7717/peerj.20146", "study": "Effectiveness of multi…

source_9c57154dfc704357

{"content_hash": null, "edges": [{"from": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "to": "claim_1", "type": "contains_claim"}, {"from": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "to": "claim_2", "type": "contains_claim"}, {"from": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "to": "claim_3", "type": "contains_claim"}, {"from": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "to": "claim_4", "type": "contains_clai…

source_7f969b8ad1774ed7

{"contradictions": ["The conclusion is that longevity metabolism effects remains a bounded geroscience case: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "13 included sources were assigned to this outcome class. Directional coding: mixed=1, null=12. Directness coding: indirect=10,…

source_d5bfc18da5034ef1

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
"Effects of resistance-based training and polyphenol supplementation on physical function, metabolism, and inflammation in aging individuals",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effectiveness of multi-component exercise in individu…

source_548dffd75f694642

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "439fc1a1-66aa-4252-a6f9-14ba1bb1860c", "sources": [{"directness": "primary", "doi": "10.1007/s11357-025-01839-8", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of resistance-based training and polyphenol supplement…

source_42b40bedae6a4810

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}