Derivation Web

claim_a8293dcbc8614223

# Alpha memo — exercise

**Headline:** Exercise: single-source lead signal with broader context receipts
**Alpha triage:** `high` (internal ranking; not a certainty claim)
**Confidence:** `evidence_backed_signal`
**Memo surface:** `alpha memo`
**Snapshot:** `2026-05-16T18-12-38Z`
**Run:** `exercise-evidence-2026-05-16T18-12-38Z`
**Direct source breadth:** `1` direct cited source(s)
**Source thesis…

source_6ddcb263ec714b7e

# Alpha memo — exercise

**Headline:** Exercise: single-source lead signal with broader context receipts
**Alpha triage:** `high` (internal ranking; not a certainty claim)
**Confidence:** `evidence_backed_signal`
**Memo surface:** `alpha memo`
**Snapshot:** `2026-05-16T18-12-38Z`
**Run:** `exercise-evidence-2026-05-16T18-12-38Z`
**Direct source breadth:** `1` direct cited source(s)
**Source thesis…

source_9450a04db3144c50

{"publication_id": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "traces": [{"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle followin…

source_8aa555f38e5f44a9

{"content_hash": null, "edges": [{"from": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "to": "claim_1", "type": "contains_claim"}, {"from": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "to": "claim_2", "type": "contains_claim"}, {"from": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "to": "claim_3", "type": "contains_claim"}, {"from": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "to": "claim_4", "type": "contains_clai…

source_9f42bd59c90347b1

{"contradictions": ["The useful signal is narrower than the topic label: the lead receipts support the core claim, while the added A/B context receipts define where that claim may generalize, fail, or need a separate extraction.", "`fact_id=12572` (`A_core`) — Mixed-muscle protein fractional synthetic rate increased by 42% at 3 h postexercise and 69% at 24 h postexercise in CON. DOI `10.1152/ajpen…

source_2e548c9cc41e41b7

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Activation of mTORC1 signaling and protein synthesis in human muscle following bl…

source_24a122b34d5a476b

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "d2507e5a-e8e6-4a30-aa39-33d2478faccc", "sources": [{"directness": "primary", "doi": "10.1158/1940-6207.capr-20-0188", "risk_of_bias": "not appraised in public sidecar", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammat…

source_84991a7821b54981

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}