Derivation Web

claim_c88b148e5d524623

# Research Synthesis: Fasting Regimens — full paper

## Abstract

Evidence-honesty note: 11/14 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statement that the…

source_f760a4be901a4d89

# Research Synthesis: Fasting Regimens — full paper

## Abstract

Evidence-honesty note: 11/14 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a statement that the…

source_ae354d0554cf4ec6

{"publication_id": "e64257d3-7980-4e68-9b2d-12e06cf91b11", "traces": [{"candidate_sources": [{"doi": "10.3390/nu18020238", "study": "Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting: A 12-Month Randomized Trial in Adults with Obesity", "url": "https://doi.org/10.3390/nu18020238"}, {"doi": "10.3390/nu18111799", "study": "Age-Specific Analysis of the Effects of Intermitten…

source_568d111fac624df4

{"content_hash": "sha256:d1081645009b2a6aa6825e72470f8d186d685428562cb2bd0eafc9ae85566a8a", "edges": [{"from": "e64257d3-7980-4e68-9b2d-12e06cf91b11", "to": "claim_1", "type": "contains_claim"}, {"from": "e64257d3-7980-4e68-9b2d-12e06cf91b11", "to": "claim_2", "type": "contains_claim"}, {"from": "e64257d3-7980-4e68-9b2d-12e06cf91b11", "to": "claim_3", "type": "contains_claim"}, {"from": "e64257d3-…

source_74df734993de405e

{"contradictions": ["The conclusion is that fasting regimens should be treated as a bounded geroscience hypothesis: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "10 included sources were assigned to this outcome class. Directional coding: mixed=1, negative=1, null=8. Directness co…

source_113fd2f11f9747ac

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting: A 12-Month Randomized Trial in Adults with Obesity,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Age-Specific Analysis of the Effects of Intermittent Fasting o…

source_1ac20481765a46b0

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "e64257d3-7980-4e68-9b2d-12e06cf91b11", "sources": [{"directness": "review-level", "doi": "10.3390/nu18020238", "risk_of_bias": "not appraised in public sidecar", "study": "Metabolic and Orexin-A Responses to Ketogenic Diet and Intermitte…

source_ffd2e7260a604a3b

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}