Derivation Web

claim_d0e231ce6a8f4340

# Adjacent Evidence Brief: Longevity Lifespan Rates — full paper
## Abstract

Evidence-honesty note: 7/13 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a stateme…

source_7541446543f64959

# Adjacent Evidence Brief: Longevity Lifespan Rates — full paper
## Abstract

Evidence-honesty note: 7/13 retained sources are coded as null or no extracted directional signal; this corpus is non-supportive for clinical efficacy claims and hypothesis-generating only. Source-bundle reconciliation note: Directional coding is conservative claim-level coding from extracted claim records, not a stateme…

source_e1dd8892a2fd4a9a

{"publication_id": "6eba8bfc-d1b3-4094-a4b1-155f1a96a6a0", "traces": [{"candidate_sources": [{"directness": "primary", "doi": "10.1002/advs.202511813", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining…

source_632e18af9360488a

{"content_hash": "sha256:9e925a5e25875012be311203e83191e478a7bc25ab398efc75726b678482503d", "edges": [{"from": "6eba8bfc-d1b3-4094-a4b1-155f1a96a6a0", "to": "claim_1", "type": "contains_claim"}, {"from": "6eba8bfc-d1b3-4094-a4b1-155f1a96a6a0", "to": "claim_2", "type": "contains_claim"}, {"from": "6eba8bfc-d1b3-4094-a4b1-155f1a96a6a0", "to": "claim_3", "type": "contains_claim"}, {"from": "6eba8bfc-…

source_ba085cb2b2a647ba

{"contradictions": ["The conclusion is that longevity lifespan rates remains a bounded geroscience case: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "Direction reconciliation: receipt-level null or unclear coding is conservative claim-level coding. Significant but polarity-unsign…

source_5d8e9b6aa0b2482b

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Developmental disruption of the mitochondrial fi…

source_8678a713a0674499

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "6eba8bfc-d1b3-4094-a4b1-155f1a96a6a0", "sources": [{"directness": "primary", "doi": "10.1002/advs.202511813", "risk_of_bias": "not appraised in public sidecar", "study": "Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Org…

source_c3ab0a683d604e56

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}